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KMID : 0882420050680010105
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Korean Journal of Medicine
2005 Volume.68 No. 1 p.105 ~ p.110
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Two cases of primary hepatocellular carcinoma with skull metastasis
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Kim Yun-Soo
Kim Young-Seok
Lee Moon-Sung
Hong Dae-Sik
Shim Chan-Sup
Kim Boo-Sung
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Abstract
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Primary hepatocellular carcinoma (HCC) is one of the most common tumors in the world. HCC often metastases to the lung and the regional lymph nodes, but rarely to the bones. The most frequent sites of skeletal metastasis are the rib, spine, femur, pelvis and humerus, but the metastasis to the skull is very rare in HCC. Especially, the metastasis to the skull alone, or skull mass presented as first sign in Hcc is extremely rare. We report a 74-year-old female who had HCC with the solitary skull metastasis and a 42-year-old male with HCC presented skull metastasis as the initial clinical manifestation.
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KEYWORD
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Hepatocellular carcinoma, Skull metastasis
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